Seminars:

Dr. Jill Keith "The Synthesis and Biological Evaluation of Diphenylmethoxypiperidines (DPP)

Dr. Bita Nickkholgh "Regulation of Protein kinase D1: A tumor suppressor gene in prostate cancer"

Research is based on the chemical imbalances in the neurotransmitters, dopamine, serotonin, and norepinephrine resulting in pathological conditions such as depression, bipolar disorder, etc. Dr. Keith research is to provide a drug what will wean addicts off of cocaine, a pathological condition. The drugs are known for going through a process of DA synthesis, release, binding, and reputake. Cocaine is known to inhibit dopamine for about thirty minutes increasing the sensation of the drug. The method Dr. Keith is using is the alignment of cocaine with (DPP). In order for the pyridine to replace cocaine, Keith had to get rid of the ketone, two carbon bridge, and ester. The pyridine is known for lasting longer than cocaine.

Dr. E.xazevia Logan "The Effects of PI3 Kinase Signal Transduction Pathways on Cardiovascular Function"

Purpose of research is to find a treatment for hypertension through microinjections of PI3 Kinase inhibitor into the brain. Results showed that Wortmannin reduces blood pressure in Lewis and mRen2. However, still determining the side effects, how long the microinjection will last, and signs of tumors.

Dr. Frank Booth "Physical inactivity is a contributing cause to at least 40 unhealthy conditions"

Research reflected on how inactivity on Earth increases abdominal fat. His experiment consisted of running rats on wheels for approximately 21 days and then locking the wheel to restrain the rat. The more exercise, the lower fat percentage the rat had within its abdominal area. If we incorporate physical activity daily, we will live longer.

Cancer patients come back with legions in different organs due to prostate cancer. Cancer becomes resistant to the current treatment options and move on within the body. Another struggle would be no prediction model, lacking the progression and where the cancer may metastasize. The Protein Kinase D1, a protein in the body that align all kinases to be phosphorylated. The expression of Protein Kinase D1 is low and known to down regulate the advanced stage of prostate cancer.

Scholarship Day Symposim 2016

Several seminars presented by biology students informing students on their findings, hypothesis, and purpose. I presented with Brittani Edwards, Arionne Walker, and Zipporah Cornelius on Historical Figure STEM - Dr. Astor Y. Herrell.The purpose of this historical figure project was for students to find out information about former students or faculty members and discover their impact here, at Winston Salem State University and towards STEM. WBA Room 210 is a well known classroom and our group came across a plaque that read “Herrell Lecture Room” Dr. Astor Y. Herrell years of service was 1979-2005, almost 30 years of service at WSSU. Throughout our research, we discovered that Dr. Herrell was invited to join a three regional workshop in 1981 that involved an opportunity for Air force research. In addition, Dr. Herrell help start the chemistry and medical technology programs here at Old State U. Without Dr. Herrell’s impact on WSSU and STEM, our chemistry department would have taken longer to create and or not been available here at Winston.